Chinaberry-Tree Bark

Mainly contains triterpenoid compounds, the principal components being toosendanin, kulactone, etc. Also contains tannins, resins, kaempferol, meliacine, and sugars, etc.

The alcoholic extract has a paralyzing effect on pig roundworms in vitro, and toosendanin is the effective component for expelling roundworms. This product also has effects of paralyzing pinworms, resisting schistosomes, and inhibiting various pathogenic fungi. Toosendanin can enhance the contraction of skeletal and smooth muscle, and large doses can cause respiratory failure in rats. Its ethanol extract has anti-ulcer, antidiarrheal, cholagogic, analgesic, anti-inflammatory, and antithrombotic effects.

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