Chinese Clematis Root

The root of Clematis chinensis contains protoanemonin and saponins whose aglycones are hederagenin, epihederagenin and oleanolic acid.

1. Analgesic effect: Hot-plate testing shows that intraperitoneal injection of Weilingxian decoction at 2.5 g/kg increases the pain threshold in mice. The wine-processed product has a stronger and longer-lasting analgesic effect. 2. Choleretic effect: Oral administration of 100% Weilingxian decoction or 200% alcoholic extract at 3–4 mL/kg promotes bile secretion in rats. Intravenous administration of 200% alcoholic extract at 0.5–1 mL/kg rapidly promotes bile secretion in anesthetized dogs and relaxes the sphincter at the end of the common bile duct, facilitating bile flow.

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