Wooly Dutchmanspipe Herb

The rhizome contains allantoin, aristolactone, mollolactone, β-sitosterol, aristolochic acid A, 9-ethoxyaristolactam and 9-ethoxyaristolactone. The stems and leaves contain aristolochic acid A, aristolochic acid D, vanillic acid, aristolactam, 6-methoxyaristolactam, palmitone, n-triacontanol, daucosterol and stearic acid.

Xungufeng has analgesic effects. Its total alkaloid fraction shows an 81.1% inhibition rate in the writhing test, while the non-alkaloid fraction shows a 53.8% inhibition rate. The alcoholic extract of Xungufeng has significant anti-implantation effects in both rats and mice. Aristolochic acid A isolated from Xungufeng has significant anti-implantation and early pregnancy-terminating activity in mice, whereas in rats it is effective only at high doses of the alcoholic extract.

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