Leaf and stem of True Indigo

The whole herb contains indican, deguelin, dehydrodeguelin, rotenol, rotenone, tephrosin, sumatrol, and histamine. The flavonoid compounds include apigenin, kaempferol, luteolin, quercetin, and indigotinone.

1. Hepatoprotective effect: Indigofera extract at 500 mg/kg can ameliorate the increase in hepatic LDH activity, decrease in urea level, and reduction in bile secretion caused by D-galactosamine and carbon tetrachloride in rats, thereby reducing liver toxicity. The ether extract FA from the aerial parts of Indigofera can antagonize CCl₄-induced liver injury. No death was observed after intragastric administration of 2 g/kg to mice. 2. Antioxidant effect: After oral administration of the ethanol extract at 500 mg/kg for 21 days to albino male rats, it antagonized the decrease in antioxidant enzyme activities and the increase in lipid peroxide content induced by D-GalN and endotoxin, thus showing antioxidant activity.

No precautions information available